Find the length of DNA by base pairs??

acorneee

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12 years ago

One species of tree has a very large genome consisting of 2.0x10^10 base pairs of DNA.
a) if this DNA was organized into a single linear molecule, how long (meters) would this molecule be?
b) If the DNA is evenly distributed among 10 chromosomes and each chromosome has one origin of DNA replication, how long would it take to complete the S phase of the cell cycle, assuming that DNA polymerase can synthesize 2x10^4 base pairs of DNA per minute (both strands)?

How do you even start on that first question? I can't find anything online or in my notes that even hint at finding the length of DNA by any means other than electrophoresis. The second question is way beyond my head.

Any help?

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lewis

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Valued Member

12 years ago

(a) (34 nm/100bp) (2 × 1010 bp) = 6.8 × 109 = 6.8 meters.

(b) 2 × 1010/10 chromosomes = 2 × 109 bp
4 × 104 bp/min (bidirectional); 2 × 109/4 × 104 = 5 × 104 min = 50,000 min.

View all three attachments for the solutions to the whole chapter Slight Smile

(Specifically, chapter 10)

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lewis

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Valued Member

12 years ago

Chapter 1 and 6 solutions

Attached file(s)

Prob_Sol_ch01.rtf (1494.42 KB)

Prob_Sol_ch6.rtf (5461.63 KB)

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acorneee Author

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12 years ago

Oh, fantastic. Okay, I see how it works now. Thanks lots! Waving Hand Sign

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lewis

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Valued Member

12 years ago

Quote from: acorneee (12 years ago)

Oh, fantastic. Okay, I see how it works now. Thanks lots! Waving Hand Sign

I'll be uploading chapter 10 solutions (which is where I found this one) in a while, just remind me. The file has all solutions from that section Smiling Face with Open Mouth

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