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BreakFree BreakFree
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9 years ago
The nurse explains to a student nurse that the median lethal dose of drugs is often determined in laboratory preclinical trials. Which rationales best support why this is done?


1. It would be unethical to determine these values in human subjects.
2. The safety of the medication must be determined prior to clinical trials.
3. It is difficult to obtain sufficient participants for clinical trials.
4. Clinical trials determine only the effective dose of a drug.
5. It is too costly to conduct the studies during clinical trials.
Textbook 
Pharmacology: Connections to Nursing Practice

Pharmacology: Connections to Nursing Practice


Edition: 3rd
Authors:
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3 Replies
First-year pharmacology student, representing MIT!
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Answer verified by a subject expert
nginngin
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9 years ago
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BreakFree Author
wrote...
9 years ago
Wow! Thanks, for the rationale and reasoning, makes total sense.
First-year pharmacology student, representing MIT!
wrote...
9 years ago
No problemo! I knew you would appreciate the reasoning.
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