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pinkish rosey pinkish rosey
wrote...
13 years ago Edited: 13 years ago, pinkish rosey
If you have 168 micro litre of a solution of lipid (e.g., DMPC) at a concentration of 80158 micro g/ml in water, you can make in theory more than 5.3817 x 10^13 liposomes having a diameter of 100 nm. (Assume a cross-section area of each molecule of lipid of 37 Å squared and a molecular weight of the lipid of 983 Da). True or false?

Can you show the calculation?
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wrote...
#1
Educator
13 years ago
Hey pinkish rosey, this is indeed a difficult one to answer. Have you tried using the formula:

Nlipo = (Mlipid X NA) / (Ntotal X 1000)



NA is the Avogadro number and it is equalto 6.02 X 1023,
Mlipid is the molar concentration of lipid
Ntotal is the total number of lipids perliposome

Check this website out:

http://www.liposomes.org/2009/01/number-of-lipid-molecules-per-liposome.html
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