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muratuba muratuba
wrote...
Posts: 45
Rep: 3 0
11 years ago
A 150 lb, 62 year-old man had a chronic productive cough, exertional dyspnea, mild cyanosis, and marked slowing of forced expiration. His pulmonary function and laboratory tests follow:
 Frequency 16 breaths/min
 alveolar ventilation 4.2 L/min (Assume 150 ml anatomical dead space)
 vital capacity 2.2 L
 functional residual capacity 4.0 L
 total lung capacity 5.2 L
 maximum inspiratory flow rate 250 L/min
maximum expiratory flow rate 20 L/min
 PaO2 62 mm Hg
 PaCO2 39 mm Hg
 Pulmonary function tests after bronchodilator therapy:
 frequency 16 breaths/min
 alveolar ventilation 4.35 L/min
 VC 2.4 L
 FRC 4.0 L
 TLC 5.2 L
 Max inspiratory flow rate 250 L/min
 max expiratory flow rate 23 L/min
 PaO2 62 mm Hg
 PaCO2 38 mm Hg
 Questions:
 1. What is the disorder this man has?
 2. Is this primarily a restrictive or obstructive disorder? Why?
 3. Why is the bronchodilator therapy ineffective in this man?
 4. What causes hypoxemia?
 5. Calculate the residual volume (RV) for this person before and after the bronchodilator therapy.
 6. What is the cause of this altered RV?
 7. Calculate the tidal volume (TV) for this man before and after the bronchodilator therapy.
 8. Is each TV normal or altered?
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5 Replies
TAD

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Replies
wrote...
Staff Member
11 years ago
1. What is the disorder of this 62-year-old man?

The disorder of this individual is emphysema.

2. Is this primarily a restrictive or an obstructive disorder? Why?

This is primarily an obstructive disorder with mild restriction as demonstrated by the maximum inspiratory flow rate (63% of normal) and maximum expiratory flow rate (7% of normal).

3. Why is the bronchodilator therapy ineffective in this man?

The bronchodilator therapy is ineffective in this man because he does not have bronchoconstriction; instead there is alveolar destruction with increased RV and FRC.

4. What causes the hypoxemia?

The causes of the hypoxemia are an increased FRC or RV and a decreased alveolar surface area available for gas exchange.

5. Calculate the residual volume (RV) for this person before and after the bronchodilator therapy.

RV = TLC - VC. The RV for this person before bronchodilator therapy is 3.0 L and after is 2.8 L. (Normal RV is 1.2 L.)

6. What is the cause of this altered RV?

Loss of elastic recoil by the "emphysemic" alveoli results in an increased physiologic dead space volume, thus increasing the RV.

7. Calculate the tidal volume (TV) for this person before and after the bronchodilator therapy.

A normal tidal volume = 500 ml/breath-so each above TV is altered.

8. Is each TV normal or altered?

A normal tidal volume = 500 ml/breath-so each above TV is altered

9. Calculate the minute ventilation (MV) for this person before and after the bronchodilator therapy.

MV = TV x f

MV before bronchodilator therapy = 6.6 L/min.
MV after bronchodilator therapy = 6.75 L/min.

10. Is each MV normal or altered?

A normal minute ventilation = 5 - 9 L/min-so each above MV is normal.
- Master of Science in Biology
- Bachelor of Science
muratuba Author
wrote...
11 years ago
thank you so much duddy Person Raising Both Hands in Celebration
TAD
wrote...
Staff Member
11 years ago
NP

Don't forget to make a contribution by uploading your labs, etc.
- Master of Science in Biology
- Bachelor of Science
muratuba Author
wrote...
11 years ago
Ok, I never do the copy paste, those info are cue Wink Face Wink Face Wink Face
thank you...
TAD
wrote...
11 years ago
How did you get the TV?
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