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Home Q & A Board Science-Related Homework Help High School Level Science
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rivertube rivertube
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12 years ago
You are studying a population of 100 people and discover that 36 of these people are ss for a genetic condition. Use the Hardy-Weinberg equation to figure out the frequencies of the S and s alleles. What are the frequencies of the SS, Ss, and ss genotypes?
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#1
12 years ago
In its simplest form the Hardy-Weinberg formula may be stated thus: If p is the proportion of gene A in the population and q(= 1 ? p) is the proportion of gene a, then after one generation of random mating the three genotypes AA, Aa, and aa will occur in the proportions p2, 2pq, and q2. In other words the genotypes are given by the appropriate terms in the expansion of the binomial (p + q)2. The extension to multiple alleles is direct.
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#2
12 years ago
Austin C is correct, but in case you need some help getting to an answer:

If q is the frequency of the recessive allele, s, in the population, then the frequency of the recessive homozygotes is given by q^2:

q^2 = 36/100 = 0.36
q = 0.6

Since p + q = 1, you can find p.

Further, you can find the frequencies of the SS and Ss genotypes, since p^2 is the frequency of dominant homozygotes in the population and 2pq is the frequency of heterozygotes in the population.

Good luck!
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