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Home Q & A Board Biology-Related Homework Help Cell Biology
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oallauddin oallauddin
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11 years ago
For instance, if a bacteria develops penicillin resistance, does this mean the # of  PBP's in the cell wall are reduced, or does the bacterial cell wall structurally evolve in that penicillin can no longer bind to the PBP and therefore the integrity of the bacterial cell wall remains intact preventing lysis?
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11 years ago
Antibiotic resistance can be caused by:
1.structural change in affected protein
2.development of system that pumps antibiotic out of the cell (therefore antibiotic cannot take effect inside the cell)
3. production of anti-antibiotic chemicals

In case of change in PBPs the only thing that changes is the structure of PBPs. Their structure is modified in a way that penicillin cannot bind to them.
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