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rjedlicka rjedlicka
wrote...
Posts: 97
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12 years ago
Assume a population in Hardy-Weinberg equilibrium for a character trait with these genotypic frequencies: AA = 0.25, Aa = 0.50, and aa = 0.25. If you remove all the homozygous dominants and allow the remaining population to reproduce (again under Hardy-Weinberg conditions), what will be the frequency of homozygous dominants in the next generation?

Please explain
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RJW
wrote...
12 years ago
There wouldn't be any. Make a Punnett square to see why. If you're removing the homozygous dominants (AA) you're only left with Aa and aa as options.

___a_|__a__
A| Aa |  Aa
a| aa  | aa

You can't get AA when one parent is homozygous recessive.
wrote...
12 years ago
Try this:

Say there is a population of 100 with those frequencies:  25, 50, 25.  We'll remove the dominant homozygotes (25) leaving a population of 75.  The frequency of aa is now 0.33 and of Aa is 0.67.  So, we can do Hardy-Weinberg calculations based on a frequency of 0.33 of aa, which means the frequency of a is 0.57, which we let = q;  the frequency of A is 0.43 = p.

Hardy-Weinberg equation #2 says that the frequency of AA is now 0.18, the frequency of Aa is now 0.49, and teh frequency of aa is 0.32.

The frequency of dominant homozygotes is 0.18;  dominant homozygosity isn't as popular as it used to be...
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