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Home Q & A Board Science-Related Homework Help Chemistry (Moderator: Laser_3)
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david1088 david1088
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11 years ago
Reactions such as:
HCl and R-OH,
PCl3 and R-OH,
PCl5 and R-OH,
And SOCl2 and R-OH.
Please help thanks loads.
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wrote...
#1
11 years ago
My best guess is that OH groups are not good leaving groups and do not ready leave without being made into a better leaving group first.  usually the OH has to be protonated or must combine with a tosyl group to become a better leaving group before being kicked off.  

My 2 cents
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