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13 years ago
A chronotropic agent is one that affects the heart rate. Compare and contrast this term with an inotropic agent. Give specific examples of each.
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Human Physiology: An Integrated Approach

Human Physiology: An Integrated Approach


Edition: 8th
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13 years ago
Inotropic agents affect contractility. Catecholamines ( epinephrine, norepinephrine) and drugs such as digitalis are positive inotropic agents, meaning they increase contractility. Heart rate is increased by epinephrine (a positive chronotropic agent) and decreased by acetylcholine (a negative chronotropic agent); there is also a variety of drugs that affect heart rate.
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