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placenamehere placenamehere
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11 years ago



1. If a fly cell (2n=8) underwent meiosis I and meiosis II and produced:

2 gametes with 4 chromosomes each,
1 gamete with 3 chromosomes, &
1 gamete with 5 chromosomes


Which statement is correct?

a.) all four daughters cells produced are aneuploids
b.) a nondisjunction occurred in Anaphase I
c.) a nondisjunction occurred in Anaphase II
d.) all four daughter cells can fertilize/ be fertilized and produce normal offspring
e.) none of the above are correct




2. The normal daughter of a man with hemophilia (a recessive, sex-linked condition) marries a man who is normal for the trait.

What is the probability that a daughter will be a hemophiliac?


What is the probability that a son will be hemphilliac?


If the couple has two sons, what is the probability that both sons will be born with hemophilia?





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11 years ago
1
In this picture:
http://www.google.gr/imgres?imgurl=http://img.tfd.com/dorland/thumbs/nondisjunction.jpg&imgrefurl=http://medical-dictionary.thefreedictionary.com/Meiotic%2Bnondisjunctions&h=387&w=250&sz=17&tbnid=QAhfw9QCTpOEWM:&tbnh=90&tbnw=58&prev=/search%3Fq%3Dmeiosis%2Bnondisjunction%26tbm%3Disch%26tbo%3Du&zoom=1&q=meiosis+nondisjunction&usg=__DXTbh4ibkW7TDKkUIj3xmW8kYkc=&docid=k12PVVYHv9v01M&hl=en&sa=X&ei=GzvGUPnsN8WztAao8oCwAw&sqi=2&ved=0CCkQ9QEwAQ&dur=1433

A is the normal meiosis
B is a meiosis where a nondisjunction occurred in Anaphase I
C is a meiosis where a nondisjunction occurred in Anaphase II

As you see, if a nondisjunction had occurred in Anaphase I, then you would have two cells with one (or more) extra chromosome(s), and two cells with one (or more) less chromosome(s). So b) is wrong.
If a nondisjunction had occurred in Anaphase II, then you would have two cells with the correct number of chromosomes, a cell with one (or more) extra chromosome(s), and a cell with one (or more) less chromosome(s).

So the correct answer is c.

(here is a picture where all the steps of meiosis are shown: http://en.wikipedia.org/wiki/File:Meiosis_diagram.jpg)

2
A man with hemophilia has a genotype: XaY   (Xa is the pathological allele, and X is the normal allele)

His daughter will receive the Xa allele from her father, and a normal X from her mother.

She marries a normal man, so we have the crossing:
XXa  x  XY

children: 25%XX, 25%XY, 25%XXa, 25%XaY.

The Xa allele is recessive, so only the male child will have hemophilia. (0% of the daughters, 50% of the sons)

The probability of the two sons to have hemophilia is (1/2)*(1/2)=1/4=25%
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