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colleen colleen
wrote...
Valued Member
Posts: 17076
11 years ago
A nurse is teaching a nursing student about the effects of a sustained drop in systemic blood pressure on the juxtaglomerular cells of the distal tubules in the kidneys. The nurse knows teaching has been effective when the student states, “This juxtaglomerular cell response to low blood pressure is utilized with the medication
1. captopril (Capoten).”
2. digoxin (Lanoxin).”
3. furosemide (Lasix).”
4. adenosine (Adenocard).”
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Sunshine ☀ ☼

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wrote...
Valued Member
11 years ago
1 -- A sustained drop in systemic blood pressure triggers the juxtaglomerular cells to release renin. Renin acts on a plasma globulin, angiotensinogen, to release angiotensin I, which is in turn converted to angiotensin II. As a vasoconstrictor, angiotensin II activates vascular smooth muscle throughout the body, causing systemic blood pressure to rise. Captopril (Capoten) is an ACE inhibitor, which blocks the conversion of angiotensin I to the vasodilator angiotensin II. The other drugs are not ACE inhibitors.
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