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12 years ago
Erythrocytes (red blood cells) have no nucleus, mitochondria, or other organelles are ejected when the RBC enters the bloodstream, or shortly thereafter. Should this still be considered a cell? What will be the effect of having no nucleus? In these cells, the lack of mitochondria is an advantage. why?
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wrote...
12 years ago
> Should this still be considered a cell?
That's an opinion question, and my opinion is "no."
It's a bag of hemoglobin.  No metabolism.  Not alive.
I try not to call it "cell" and instead use the terms "erythrocyte" and "corpuscle."> What will be the effect of having no nucleus?> the lack of mitochondria is an advantage. why?
Minimal chemistry going on in there.  No manufacture of new proteins.  Anaerobic glycolysis only (not using the oxygen they're carrying).
Lacking these things means that the erythrocyte has one function:  carrying gases using hemoglobin.

It is very good at that.  Without the organelles, it's more bendable and can fit through smaller capillaries (bird red blood cells have nuclei, and birds have larger capillaries than mammals).
wrote...
12 years ago
yes. RBCs are considered cells. the effect of having no nucleus is that there will be no cell activities such as cell division. the nucleus controls gene expression and mediates DNA replication during the cell cycle. since they don't have a nucleus, they cannot synthesis proteins. thats the reason why RBCs are manufactured in the red bone marrow. the other reason why they don't have a nucleus is to maximize the size of oxygen that is carried by hemoglobin.
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