× Didn't find what you were looking for? Ask a question
Top Posters
Since Sunday
n
3
j
3
x
2
c
2
2
p
2
n
2
3
2
C
2
z
2
k
2
d
2
Home Q & A Board Biology-Related Homework Help Cell Biology
New Topic  
rixter119 rixter119
wrote...
Posts: 102
Rep: 3 0
11 years ago
Also...where in the cell would you expect the insulin receptor to reside? Why?
Read 783 times
2 Replies

Related Topics

Replies
wrote...
#1
11 years ago
Hormone receptors (like the estrogen receptor) are soluble receptors (they float around in the cytoplasm). Most hormones are low-molecular-weight and fat-soluble, so they can easily cross the plasma membrane.

The insulin receptor is a trans-membrane receptor (it's on the cell's surface). Insulin itself is a polypeptide (i.e. it has a high molecular weight -- ~5 kDa -- and is charged) and cannot easily cross the plasma membrane.
wrote...
#2
11 years ago
Steroids are lipid-soluble and therefore easily cross cell membranes.Steroid hormone receptors are found in the cytoplasm of the cell. Upon binding, the resulting complex then travels into the nucleus and works with the DNA to produce whatever proteins it's programmed to produce.
Insulin receptors are on the membrane because insulin is a protein and is not soluble in lipids, so it can only act on the surface, allowing glucose to enter cells.
The answer to life, universe and everything is 42 Slight Smile
New Topic      
Quick Reply
Explore
Post your homework questions and get free online help from our incredible volunteers
  919 People Browsing
Start New Topic Take the Tour CoursesNew Study Tools Topics Trending Browse by Textbook
Live Chat
Related Images
  
 431
  
 626
  
 8821
Your Opinion
What's your favorite funny biology word?
Votes: 329
Previous poll results: Where do you get your textbooks?