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awluxllc awluxllc
wrote...
Posts: 24
Rep: 8 0
11 years ago
I dont understand this stuff at all.  can someone please help, i have a couple of questions like this.  thanks.

Using the following DNA segment, the RNA transcribed and the translation

DNA 5'  ATG TTC GGG CCT AAC TGC CCG GGA AGG TGA 3'
DNA 3'  TAC AAG CCC GGA TTG ACG GGC CCT TCC ACT 5'

RNA 5' AUG UUC GGG CCU AAC UGC CCG GGA AGG UGA 3'
Protein  met  phe   gly     pro   asn   cys    pro    gly    arg      x

DRAW an example of each of the following (circle the nucleotide that has changed):

A Missense Mutation:

A Frameshift Mutation:

A Point Mutation:
Source  Prescotts Microbiology 8th edition
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wrote...
Educator
11 years ago
A Missense Mutation: One nucleotide changes, leading to a new amino acid...

DNA 3' TAC AAG CCC GGA TTG ACG GGC CCT TCC ACT 5'

Upwards Arrow This is the strand that is being transcribed. So, let's change one of its nucleotides:

DNA 3' TAC ACG CCC GGA TTG ACG GGC CCT TCC ACT 5'

This results in:

RNA 5' AUG UGC GGG CCU AAC UGC CCG GGA AGG UGA 3'

Protein  met  cys   gly     pro   asn   cys    pro    gly    arg      x

Therefore, phe becomes cys (cysteine).
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