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colleen colleen
wrote...
Valued Member
Posts: 17077
11 years ago
A patient states “My doctor said sometimes I would have an on/off problem with this medication what does that mean?” The best response by the nurse is which of the following?
1. “The on times will be when your symptoms are under control; the off times are when you will have increased problems with symptom management.”
2. “There will be times when you are depressed (off) and when you are happy (on).”
3. “You will have to take breaks from this medicine by stopping (off) and starting it (on) again, so you don’t build up a tolerance to it.”
4. “I’m not a pharmacist, so I shouldn’t be answering this question.”
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Sunshine ☀ ☼

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Replies
wrote...
Valued Member
11 years ago
1 -- Patients taking Parkinson’s drugs can experience episodes of hypomobility (off) when the dopamine/acetylcholine are imbalanced, and periods of symptom management when these two neurotransmitters are in better balance the on time. On/off phenomenon has nothing to do with depressive episodes, and the medication for Parkinson’s should not be started and stopped. A nurse should be able to answer questions about the patient’s medications, or at least attempt to find the answer if it is not known.
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