Ex 3 Physio-EX 8.0. Nerve inhibition with curare

taffy

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13 years ago

Ex 3 Physio-EX 8.0. Nerve inhibition with curare

I teach this lab to Physiology students and had run through most of this while teaching this summer. We just added this particular simulation exercise to our Physio Lab this fall. I don't remember how the curare part worked last time, but do know that when I treated the nerve with curare this time, I was still able to generate an action potential with 3.0 mv. I want to tell myself this is to be expected because the inhibition is after the terminal end fibers transmission of acetylcholine. Curare blocks the receptor sites on the next nerve or muscle cell membrane. However the key says that you don't get an action potential. I just did it again before I sent this. Please help. I have to do this with one of my five labs at 9:30.
taffy

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how_mendel

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13 years ago

Sorry, what's the specific question. I looked for Nerve inhibition with curare in the manual and nothing turned out! Neutral Face

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Biology!

Kborum

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13 years ago

I am taking this class now and I too was able to generate action potential at 3.0V. I went along with it because I assumed it was right, however it is, like you said, supposed to block the receptors. :/ Im hoping to see a good reply to this as well! Confounded Face

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Kborum

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13 years ago

Quote from: howard (13 years ago)

Sorry, what's the specific question. I looked for Nerve inhibition with curare in the manual and nothing turned out! Neutral Face

Howard the question is
10. What was the effect or curare on eliciting an action potential?
THEN
11. Explain the reason for your answer in question 10 above.

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