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. One virus preferentially infects macrophages and is called M-tropic. The other preferentially ...

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. One virus preferentially infects macrophages and is called M-tropic. The other preferentially ...

. One virus preferentially infects macrophages and is called M-tropic. The other preferentially infects T cells and is called T-tropic. The M-tropic viruses use CCR5 and CD4 as coreceptors, and the T-tropic viruses use CXCR4 and CD4 as coreceptors. The M-tropic viruses are found early in HIV infections; the T-tropic viruses are found late in infections, when AIDS symptoms are prevalent. T-tropic viruses are associated with a drastic decrease in T cells. Macrophages go to the site of wounds, where they are used to fight infections. T cells circulate in the body and fight infections at many sites.

29) Which receptors for HIV would you expect to find on macrophages and T cells?
A) CCR5 and CD4 on macrophages; CXCR4 and CD4 on T cells
B) CCR5 and CXCR4 on macrophages; CD4 and CXCR4 on T cells
C) CD4 and CXCR4 on macrophages; CXCR4 and CD4 on T cells
D) CXCR4 and CD4 on macrophages; CCR5 and CD4 on T cells

Textbook

Biological Science, Canadian Edition

Edition: 2^nd

Authors: Freeman, Shar, Harrington

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