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KaitW KaitW
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Posts: 3
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12 years ago
HELP! I really need help with a couple of questions  The ones that are blank are the ones I need help with!

1.   Why don’t the terms depolarization and action potential mean the same thing?
Action potential is quick depolarization followed by a repolarization. Depolarization is only a one way trip. It also takes a lot of depolarization to cause action potential.

2.   What was the threshold voltage in Activity 1?

3.   What was the effect of increasing the voltage? How does this change correlate to changes in the nerves?


4.   How did the action potential generated with the unheated rod compare to that generated with the heated rod?

5.   Describe the types of stimuli that generated action potential.


6.   If you were to spend a lot of time studying nerve physiology in the laboratory, what type of stimulus would you use and why?

7.   Why does the addition of NaCl elicit an action potential?
It increases the concentration of sodium ions outside of the cell. The concentration gradient is increased even more than what it is usually at the resting potential. With that as the driving force, an action potential occurs.

8.   What was the effect of ether on eliciting an action potential?
Activation of human ether- medicates cardiac potential, depolarization.

9.   Does the addition of ether to the nerve cause any permanent alteration in neural response?
No, just temporary.

10.   What was the effect of curare on eliciting an action potential?
It inhabits action potential because curare is a toxin.

11.   Explain the reason for your answer above.
Because it is a toxin.

12.   What was the effect of lidocaine on eliciting an action potential?
There is no action potential when blocked.


13.   What is the relationship between size of the nerve and conduction velocity?
Unmyelinated nerves relationship between axon diameter and conduction velocity. Large diameter nerve conducts faster.

14.   Keeping your answer to question 13 in mind, how might you draw an analogy between the nerves in the human body and electrical wires?

15.   How does myelination affect nerve conduction velocity? Explain, using your data from chart 1.
It will speed nerve conduction velocity considerably. Myelin is found in Schwann cells which encircle a given axon.

16.   If any of the nerves used were reversed in their placement on the stimulating recording electrodes, would any differences be seen in conduction in velocity? Explain.
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Valued Member
12 years ago
3.   What was the effect of increasing the voltage? How does this change correlate to changes in the nerves?

Increasing voltage results in depolarization of increasing numbers of neurons in a nerve.

12.   What was the effect of lidocaine on eliciting an action potential?
There is no action potential when blocked.

Lidocaine is a sodium channel antagonist and will block sodium ion channels from working, preventing the generation of an action potential.
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