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shawn-dog shawn-dog
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10 years ago
Can you explain why incrasing extracellular k+ reduces the net diffusion of K+ out of the neuron through k+ leak channels?
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wrote...
10 years ago
Hi shawn-dog,

Potassium leak channels depend on the concentration difference. If you increase the concentration of K+ outside the cell, the difference between the concentration inside and outside of cell would decrease. As a result, the net diffusion of Potassium ion would decrease.

Best,
Laser
shawn-dog Author
wrote...
10 years ago
Thanks Laser_3.
I thinking I'm getting it. Still a little confused. For starters can you tell me what the definition of concentration difference is , so I can break this down in simpler terms?  Also, am I interpeting this correctly:   K+ channels are always open right? So increasing the K+ the concentration outside the cell allows less K+ to leak out the channels? I hope I'm making sense.
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