In a world’s first researchers have converted adult cells into stem cells that regenerated into different cell types of human skin and hair follicles. The follicles produced hair shaft and could be used for hair regeneration. Is this the end of baldness?

It has to do with a single gene! More than a decade ago, researchers discovered that one gene (MC1R) on chromosome 16 plays an important role in giving people red hair. MC1R task is to make the protein melanocortin 1. This protein plays an important role in converting red pigment into black pigment. If you end up with only one mutated MC1R gene, red hair can appear in unwanted places, like your beard. When someone inherits two mutated versions of the MC1R-gene (one from each parent), less red pigment is converted into black pigment. ...

Isn't it strange, two FDA-approved drugs - topical ruxolitinib or tofacitinib - can reawaken dormant hair follicles! According to the study, within 3 weeks, mice that received topical ruxolitinib or tofacitinib had regrown nearly all their hair (right photo; drug was applied only to the right side of the mouse). Little to no hair growth occurred in control mice during the same timeframe (left photo). According to researchers at Columbia University Medical Center, inhibiting a family of enzymes inside hair follicles that are suspended in a resting state restores hair growth.

These drugs, known as JAK inhibitors have been approved to treat blood diseases (ruxolitinib) and the other for rheumatoid arthritis (tofacitinib). Both are being tested ...