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michelle101 michelle101
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9 years ago Edited: 9 years ago, michelle101
1) The M and N factors are glycoproteins that are found on the surface of red blood cells. Unlike other types of red blood cell antigens, the M and N factors do not cause antibody reactions in human blood transfusions. People with type M blood are homozygous for the M allele, and people with type N blood are homozygous for the N allele. Heterozygous individuals have type MN blood. In a study of a population of Inuit living in the Northwest Territories, 640 people had blood type M, 320 had blood type MN, and 40 had blood type N. Calculate the frequency of the genotypes in the population studied. Show all of the steps to your solutions.

2)In a second study group, the frequencies of the genotypes were 0.306 MM, 0.491 MN, and 0.203 NN. Could this second study group have, in fact, come from the previously described Inuit population?
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wrote...
9 years ago
1) Number of individuals: MM=640, MN=320, NN=40
total number of individuals=1000
Genotypic frequency of:
MM: 640/1000=0.64
MN: 320/1000=0.32
NN: 40/1000=0.04

2) Yes, this second study group come from the previously described Inuit population.
We can see that, if we multiply the genotypic frequency with 1000, we get,
0.306X1000=306
0.491X1000=491
0.203X1000=203
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