Drugs for Acne

TABLE 73.2 Drug Remarks adapalene (Differin) Retinoid»|ike compound used to treat acne formation azelaic acid (Azelex, Finacea) For mild to moderate inflammatory acne benzoyl peroxide (Clearasil, Fostex, Others) Keratinolytic available OTC: sometimes combined with erythromycin (Benzamycin) or clindamycin (BenzaClin) for acne caused by F! dares clindamycin and tretinoin (Veltin, Ziana) (ombination product with an antibiotic and a retinoid in a gel base; for mild to moderate acne ethinyl estradiol (Estinyl) Oral contraceptives are sometimes used for acne; for example, ethinyl estradiol plus norgestimate (Ortho Tri-(yclen-28) isotretinoin (Accutane) For severe acne with cysts or acne formed in small, rounded masses; pregnancy categoryX sulfacetamide sodium ((etamide, Klaron, Others) For sensitive skin; sometimes combined with sulfur to promote peeling, as in the condition rosacea; also used for conjunctivitis tazarotene (Avaqe, Tazorac) A retinoid drug that may also be used for plaque psoriasis; has antiproliferative and anti-inflammatory effects tetracyclines Antibiotics; refer to (hapter 4B tretinoin (Avita, Retin—A, Others) To prevent clogging of pore follicles; also used forthe treatment of acute promyelocytic leukemia and wrinkles Cownght @2016 Pearson Education, All Rights Reserved