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SlideshowReport

How Enzymes Act as Catalysts: Principles and Examples

Description
The transition state might be stabilized by electrostatic interactions with active site amino acids and/or metal ions, or it might be stabilized by general acids or bases.

The direction of proton transfer from the proton donor to the proton acceptor is indicated by the placement of the wide end of the dashed bond near the proton acceptor.

The GAC is a proton donor and the GBC is a proton acceptor.
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