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Outline of pathways for glucose synthesis from the major gluconeogenic precursors

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Note that both glucose and lactate are carried in the blood.

The equivalent of 11 high-energy phosphates are consumed per mole of glucose synthesized by gluconeogenesis.

The most important gluconeogenic precursors are lactate, alanine, glycerol, and propionate.

Animals cannot undergo net conversion of fat to carbohydrate.
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