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Aminotransferases

Description
Aminotransferases utilize a coenzyme, pyridoxal phosphate, that is derived from vitamin B6.

The functional part of the cofactor is an aldehyde functional group, CHO, attached to a pyridine ring.

The catalytic cycle begins with condensation of this aldehyde with the a-amino group of an amino acid, to give a Schiff base, or aldimine, intermediate.
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