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SlideshowReport

The reaction of a PLP-dependent decarboxylation to yield serotonin

Description
Glutamate, tyrosine, glycine, and tryptophan serve as neurotransmitters or precursors to neurotransmitters.

The pathway to serotonin begins with hydroxylation of tryptophan by a tetrahydrobiopterin-dependent aromatic amino acid hydroxylase, similar to phenylalanine hydroxylase.
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