Common Systems for Direct DNA Repair

Table 11.4 Common Systems for Direct DNA Repair Photoreactive repair Repair of UV-induced photoproducts catalyzed by photolyase activated by visible light Base excision repair (BER) Removal of an incorrect or damaged DNA base and repair by synthesis of a new strand segment (nick translation) Nucleotide excision repair (N ER) Removal of a strand segment containing DNA damage and replacement by new DNA synthesis Mismatch repair Removal of a DNA base-pair mismatch by excision of a segment of the newly synthesized strand followed by resynthesis of the excised segment