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SlideshowReport

The importance of histones and scaffolding proteins in the compaction of eukaryotic chromosomes.

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(a) Transmission electron micrograph of a metaphase chromosome. (b) This photomicrograph shows an entire metaphase chromosome following treatment with a high salt concentration to remove the histone proteins. The label on the left points to the scaffold that anchors the bases of the radial loops; note its similarity in length and width to (a). The label on the right points to an elongated strand of DNA.
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