The scans show the relationship between high levels of default activity and amyloid deposition, atrophy, and disrupted metabolism in the brains of patients with Alzheimer’s disease. (From Buckner, R. L., Snyder, A. Z., Shannon, B. J., et al. Journal of Neuroscience, 2005, 25, 7709–7717. Copyright 2005 by the Society for Neuroscience.)
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