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Fluorescence in situ hybridization (FISH) is a cytogenetic technique that is used to detect the ...
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Fluorescence in situ hybridization (FISH) is a cytogenetic technique that is used to detect the presence or absence of specific DNA sequences on metaphase chromosomes or non-dividing (interphase) cells. FISH utilizes fluorescent DNA probes that bind to chromosomal regions with sequence complementarity. Shown here are interphase nuclei hybridized with probes for the repetitive sequences near the centromeres of the X (orange) and Y (green) chromosomes. The blue counterstain is used to identify nuclear material
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