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SlideshowReport

Protein Evolution: Myoglobin and Hemoglobin as Examples

Description
Step 1, transcription: A primary transcript (premRNA) containing complementary copies of the exons and introns is produced from the gene.

Step 2, splicing: The intron sequences are removed and the exons spliced together to yield the final mRNA.

Step 3, translation: The coding regions of the spliced mRNA produce a chain, which adopts its favored three-dimensional structure and incorporates a heme group. Note that the entire heme-binding region (red) is coded for by one exon (the central exon).
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