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SlideshowReport

Bypass 1: Conversion of Pyruvate to Phosphoenolpyruvate

Description
The bypass of pyruvate kinase begins in the mitochondrion and involves two reactions.

Pyruvate carboxylase catalyzes the ATP- and biotin-dependent conversion of pyruvate to oxaloacetate.

The enzyme requires acetyl-CoA as an allosteric activator
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