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SlideshowReport

Lipid peroxidation

Description
Superoxide per se is relatively nontoxic.

Because it contains an unpaired electron, it is a free radical, and it combines readily with another free radical, nitric oxide, a biological signaling agent that is produced in many animal tissues.

The product is peroxynitrite also considered a reactive oxygen species.

Peroxynitrite causes lipid peroxidation and also causes nitration of tyrosyl hydroxyl groups in proteins, a reaction particularly damaging to membrane proteins.
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