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SlideshowReport

Methyl-directed mismatch repair in E. coli

Description
The newly replicated daughter strand (red) contains a T mismatched to G in the template strand (blue).

The mismatch repair system identifies the daughter strand because it is not yet methylated.

Thus, this system must function before the newly replicated daughter strand becomes methylated, through action of the Dam methylase on the A residue in the GATC sequence.
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