Glomerular Filtration

Driven by blood pressure
Opposed by capsular hydrostatic pressure and blood colloid osmotic pressure
Water and small molecules move out of the glomerulus.
In one day, 150–180 liters of water pass out into the glomerular capsule.

Glomerular filtration rate – amount of filtrate formed by both kidneys each minute
Homeostasis requires kidneys to maintain a relatively constant GFR
Too high – substances pass too quickly and are not reabsorbed
Too low – nearly all reabsorbed and some waste products not adequately excreted

GFR averages 125mL/min in males and 105mL/min in females
Controlled by:
   Renal Autoregulation
   Neural Regulation
   Hormonal Regulation