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A transgenic mouse carrying a mutation in the human SOD1 gene that causes paralysis of the limbs. In

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A transgenic mouse carrying a mutation in the human SOD1 gene that causes paralysis of the limbs. In humans, the mutation causes amyotrophic lateral sclerosis (ALS), a neurodegenerative disease. The mutant mouse serves as a model for this disease, allowing researchers to explore the mechanism of the disease and to design therapies to treat humans affected with ALS.
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