Intrinsic termination

Intrinsic termination. Inverted repeat DNAsequences alone initiate transcription terminationIntrinsic termination. Inverted repeat DNAsequences alone initiate transcription termination

Termination sequence Inverted Inverted repeat 1 repeat 2 DNA-3,? ‘ Spacer sequence Polyadenine sequence 0 Intrinsic termination sequences contain inverted repeats separated by a spacer sequence and followed by a polyadenine sequence. Stem 9 Inverted repeat sequences in the transcript fold into a complementary stem ending in a single- stranded loop. Loop A A A A A A 0 Hydrogen bonds between RNA A~U base pairs break, transcript releasing the transcript and terminating transcription.