Enhancers activate transcription in cooperation with promoters

Enhancers activate transcription in cooperation with promoters. A protein bridge composed of transcriptional proteins forms between enhancer and promoter sequences, which may be separated by thousands of nucleotidesEnhancers activate transcription in cooperation with promoters. A protein bridge composed of transcriptional proteins forms between enhancer and promoter sequences, which may be separated by thousands of nucleotides

Enhancer Activator proteins Coactivator proteins Transcription start DNA bend J " ‘ ,, (dozens to ‘ thousands of '—|—' base pairs) Complete initiation complex