Antisense RNA control of the expression of IS10 transposase

Two promoters each drive the synthesis of a transcript from the IS10 transposon. The transposase gene mRNA transcript (from PIN) can hybridize with the antisense RNA transcript (from POUT) to block production of the transposase enzyme by preventing translation.Two promoters each drive the synthesis of a transcript from the IS10 transposon. The transposase gene mRNA transcript (from PIN) can hybridize with the antisense RNA transcript (from POUT) to block production of the transposase enzyme by preventing translation.

[$10 transposase mRNA 5’: 9m} :ha :—>_< 3&5, _5' POW _ 5, 3, IS10transposase _ I I I I I coding region _ 3%? [$10 antisense ’ \ RNA //’ \ // \ 1510 /,/ \ transposase mRNA 9m"? 1510 3'—5’ antisense RNA