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Home Q & A Board Biology-Related Homework Help General Biology
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mahq58 mahq58
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10 years ago
Vitamin D resistant rickets is usually an X-linked dominant condition. The disease is caused by mutations the PHEX gene and results in bone deformity and bow leggedness.

Consider a cross between a male who has vitamin D resistant rickets and a female who has fully functional PHEX protein and does not express vitamin D resistant rickets. Please use the symbol d, to denote the allele with the fully functional gene, and the symbol D, for the mutated version of the gene.

◦What are the genotypes of the described male and female?
◦What is the probability a son of this couple will inherit vitamin D resistant rickets?
◦What is the probability a daughter of this couple will inherit vitamin D resistant rickets?


I think these are the answers, please explain or help correct if these are wrong:

1. Male would carry the mutant alle on his X gene and the female would be homozygous for the functional gene (D).
2. Probability is none, a son will inherit the vitamin D resistance rickets.
3. The probability is 100% that a daughter will inherit the vitamin D resistant.
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padrepadre
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10 years ago
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mahq58 Author
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#2
10 years ago
Thanx so much for the help!!!
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