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Home Q & A Board Laboratory Help Referencing Help
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ehd123 ehd123
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Posts: 778
Rep: 54 2
9 years ago
Am I correct in thinking that because ERB (which is downregulated in cancers) downregulates c-myc ( c-myc regulatesthe cell cycle and transcription) and so this is a form of epigenetic modification?
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B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience
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wrote...
#1
Educator
9 years ago
Isn't cAMP (Cyclic AMP) what down regulates c-myc?
ehd123 Author
wrote...
#2
Valued Member
9 years ago
Not sure but maybe it plays a role downstream in the signalling cascade. The articles I read mentioned ERB (estrogen receptor beta). They said that it was significantly downregulated in breast cancer. And that there was a strong downregulation of c-myc in the presence of ERB.
B.Sc in Biology
M.Sc Neuroscience
PhD. Candidate in Neuroscience
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