How does Piracetam work?

Man, that drug is used to treat twitching, what are you doing with it and how was it prescribed to you? Do you have Parkinson's or epilepsy? If not, never take them again as this drug is fat-soluble and isn't easily removed from your body, which contributes to some side-effects you're experiencing. But regardless, an answer to your question isn't as straight forward. It is understood that piracetam interacts with receptors at the post-synaptic cleft, inflicting a modulation of ion channel and ion carriers, which will cause the neuron to enter a kind of 'excited' or facilitated state. This may well be responsible for the 'general' cognitive enhancement induced by the drug.

Well I used it for taking tests,the effect on concentration and memory was very strong,way stronger than what they said in the forums,I guess I have more of the receptors it works on or something,but I'm not sure on which receptors that is.In some places they say it acts on the GABA receptors,in other places it says it acts on the NMDA receptors and others say it affects the mitochondria or something.I wonder why some people get absolutely no effect off of it while others get a huge performance boost with no noticeable neurotoxicity symptoms,other than the fatigue and headeches which seize when the taking of the supplement is stopped.

That isn't possible, ever.


These claims are not proven. It may or may not act on them.
No two people are physiologically the same


Decrease the dosage - remember, as the saying goes, the poison is in the dose, not the quantity.

I've been interested in trying Neuro Vortex - Pramiracetam, however all the information regarding Pramiracetam (just look at Wikipedia, and you'll see) is very brief and not all that descriptive. I know that it has a few possible mechanisms of action, but what areas of the brain and what receptors exactly does it stimulate?

I've been taking Piracetam for a few years now, and have yet to experience any ill effects even when I stopped taking it for a few months while I was on Summer Vacation. I've tried doing megadoses as well when i had first started taking it and never once experienced any form of lethargy or stomach-cramps.  Piracetam effects a few areas of your brain, it stimulates your ACh Receptors as well as your GABA Receptors. The fact that it stimulates the ACh receptors is why I am considering adding Pramiracetam considering it has the reported effects of increasing your High-Affinity Choline Uptake.

There's been a lot of research regarding Piracetam, and a lot of it can be found on NIH. Most of it seems to point towards the stimulation of the GABA Receptors being Piracetam's chief mechanism of action.