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What second messenger is used by Muscarinic ACh receptors?

SmokeyV4L

wrote...

Posts: 108

Rep:

11 years ago

What second messenger is used by Muscarinic ACh receptors?

Is it specific to the type of Muscarinic receptor? (M1, M2 etc)

Read 209 times

2 Replies

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Replies

irina

wrote...

#1

11 years ago

Pretty sure it's IP3 (inositol tris-phsophate) and I ain't sure if its the same for each receptor sorry.

leleburger

wrote...

#2

11 years ago

The M1, M3 and M5 muscarinic receptors use IP3 and activation increases intracellular calcium. The M2 and M4 subtypes use cAMP as second messenger.

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