(Solved) Genome

elnerdo

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10 years ago

Knowing the complete genome of an organism doesn't necessarily tell you about the nature of all proteins in the organism. Explain why.

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zoeksyrianos

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10 years ago

Mutations occur daily to the DNA. Proteins, while are created from DNA, are more directly synthesized from RNA. The central dogma of life is DNA to RNA to protein. The DNA must be transcribed into RNA. From there, the RNA must be translated into protein. This is where things get tricky. The protein is synthesized from the mRNA (messenger RNA) when the tRNA (transfer RNA) brings a codon to the mRNA in the ribosome that corresponds to every three bases of the mRNA (A, U, C, and G). Most codons are coded by more than one specific triplet of RNA bases. You can find a table for the codons and their mRNA codes online. Because of this, you can not be sure of the nature of the protein simply by going off of the genome. Any mutation that occurs during transcription or translation can also alter the make-up of the protein.

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dgault

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10 years ago

This verified answer contains over 130 words.

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elnerdo Author

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10 years ago

dgault-- what about preteomes.. they are constantly changing (where as the DNA or genome stays the same) in response to intra- and extracellular environmental signals. Because there are tons of external factors that can affect the replicating process.. could that be enough to say that "knowing the genome won't tell you the nature of the protein"? The mutations can effect the cell's ability to produce certain types/quantities of proteins?

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bio_man

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10 years ago

Here's the way I understand what proteome is, it's the entire set of proteins expressed by a genome, cell, tissue or organism at a certain time. More specifically, it is the set of expressed proteins in a given type of cell or organism, at a given time, under defined conditions.

Quote from: elnerdo (10 years ago)

Knowing the complete genome of an organism doesn't necessarily tell you about the nature of all proteins in the organism. Explain why.

In regards to this questions, you may know that a particular sequence will code for a specific protein, but sometimes genes lie inside other genes. For example, depending on what exons get spliced together, you may get a whole different protein produced.

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