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Home Q & A Board Biology-Related Homework Help Cell Biology
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barry barry
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10 years ago
CTLA-4 is a co-stimulatory receptor on T cells that belongs to the same family as the CD28 co-stimulatory receptor.  However, CTLA-4 is antagonistic to CD28.  Which of the following could be a functional advantage of CTLA-4 expression within the immune response?

A.   CTLA-4 competes with CD28 for ligand binding so that, if CD28 binds to its ligand, the response will be magnified.
B.   CTLA-4 is often given to immunosuppressed individuals to trigger an immune response.
C.   CTLA-4 limits the immune response of TC and TH cells after an infection has been cleared.
D.   CTLA-4 limits TC activity in healthy individuals during a viral infection.
E.   CTLA-4 reduces the lag time between antigen presentation to a TH cell and B cell activation.
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padrepadre
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10 years ago
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barry Author
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#2
10 years ago
Thanks.
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