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kasy110 kasy110
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Posts: 170
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12 years ago
~ If a mistake is made, even in one nucleotide, what would you predict would occur in hemoglobin synthesis?
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kasy110 Author
wrote...
12 years ago
Never mind I think you need previous information, sorry!
wrote...
12 years ago
Major took up a post as an executive at the Standard Chartered Bank in May 1965, and he rose quickly through the ranks.
wrote...
12 years ago
A mutation would occur in the new hemoglobin produced. Example - If GAG is changed to GTG, a disease known as sickle cell anaemia occurs.

Also remember that haemoglobin is made up of four peptides and all come together in unison. One mistake and the affinity they have for one another is gone.
wrote...
12 years ago
This example is best illustrated by sickle-cell disease, in which a mutation in the hemoglobin protein is detrimental. In this disease, the substitution of a single nucleotide results in the amino acid valine being incorporated into the polypeptide as opposed to the correct amino acid, glutamic acid. This mutation causes red blood cells to assume a sickle shape, clogging blood vessels and impeding blood flow. Hence, in this case, a mistake in a single nucleotide is detrimental.
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