How will DNA replication be affected if DNA polymerase I has a mutation that inactivates 5'-to-3' ...

sms4lyfe

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6 years ago

How will DNA replication be affected if DNA polymerase I has a mutation that inactivates 5'-to-3' ...

How will DNA replication be affected if DNA polymerase I has a mutation that inactivates 5'-to-3' exonuclease activity?

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Caellis1962

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6 years ago

The 5'-to-3' exonuclease activity of DNA polymerase I removes the RNA primers from the ends of Okazaki fragments. If this activity is missing, the primers may not be removed from the growing DNA strands.

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