Which of the following statements about allosteric control of enzymatic activity is true?
A. Allosteric proteins are generally composed of a single protein.
B. Heterotropic allosteric effectors compete with substrate for binding sites.
C. Homotropic allosteric effectors compete with product for binding sites.
D. Allosteric effectors enhance the hyperbolic nature of V0 versus S kinetic plots.
E. Allosteric effectors give rise to the sigmoidal nature of V0 versus S kinetic plots.
Human chromosome 2 appears to be:
A. a fusion product of two simian chromosomes.
B. significantly different from simian chromosome 2.
C. 50 homologous to simian chromosome 2.
D. primarily coding for human traits.
Which of the following correctly describes the roles of Mg2+ ions in the polymerase reaction?
A. The first Mg2+ deprotonates the aspartate in the active site.
B. The first Mg2+ deprotonates the 3'-OH of the previous nucleotide.
C. The second Mg2+ deprotonates H2O in the active site.
D. The second Mg2+ stabilizes PPi by protonation.
E. None of these choices is correct.
Helicase PcrA follows classic Michaelis-Menten kinetics. In this reaction, ATP serves as a substrate for hydrolysis, while the DNA is most appropriately called the _____________.
A. product.
B. substrate.
C. intermediate.
D. coenzyme.
E. ligand.
Which of the following is true about haplotypes?
A. Defining a haplotype requires the identification of simple-sequence repeats (SSR) and long repetitive sequences in the human population from multiple individuals.
B. Single nucleotide polymorphisms (SNP) used to define the haplotype must be very close together on the chromosome.
C. Mitochondrial haplotypes are less stable because mitochondrial DNA recombines at a high frequency.
D. Haplotypes of the Y chromosome are not useful because only males have them.
E. Haplotypes can be used as markers to trace human migration.
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