Top Posters
Since Sunday
r
5
m
5
h
5
r
5
t
5
B
5
P
5
s
5
m
5
c
5
c
4
4
New Topic  
bogdan bogdan
wrote...
Posts: 720
Rep: 5 0
6 years ago
What role does the coenzyme A portion of acetyl-CoA play in the reaction catalyzed by citrate synthase?

A)   the CoA group causes the enzyme to close around the substrates, enabling catalysis
B)   lack of resonance in the thioester makes the methyl carbon of the acetyl group more acidic, allowing proton abstraction to readily occur
C)   CoA makes the carbonyl carbon highly susceptible to nucleophilic attack
D)   hydrolysis of the thioester makes the reaction essentially irreversible
E)   all of the above
Textbook 
Biochemistry

Biochemistry


Edition: 4th
Authors:
Read 73 times
1 Reply
Replies
Answer verified by a subject expert
incithincith
wrote...
Top Poster
Posts: 606
6 years ago
Sign in or Sign up in seconds to unlock everything for free
More solutions for this book are available here
1

Related Topics

bogdan Author
wrote...

6 years ago
this is exactly what I needed
wrote...

Yesterday
Good timing, thanks!
wrote...

2 hours ago
Brilliant
New Topic      
Explore
Post your homework questions and get free online help from our incredible volunteers
  609 People Browsing
Related Images
  
 133
  
 500
  
 341
Your Opinion