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Home Q & A Board Biology-Related Homework Help General Biology
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NAZ NAZ
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13 years ago
1)If about 105 genes are available in the human genome to produce proteins, how can we produce more than 10 ? 106 different kinds of Ab receptors (proteins) on B cells?

2)Many medicines are taken parenterally—that is, swallowed and absorbed from the digestive system. Aspirin and many antibiotics are examples. Even though these drugs may be very different chemically, the instructions for taking them often say “Repeat dose every 4 to 6 hours.” What is the reasoning behind this dose rate? In other words, why do you need to take the medicine every 4 to 6 hours? \
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13 years ago
Quote from: NAZ (13 years ago)
1)If about 105 genes are available in the human genome to produce proteins, how can we produce more than 10 ? 106 different kinds of Ab receptors (proteins) on B cells?

The information that the immune system can produce more types of B cells than there are genes in the genome begs this question. Each of the variable regions of the antibody (on both light and heavy chains) is made up of three parts. Each is coded by a different region on the DNA. The DNA segments for the three separate parts of each variable region undergo random recombination in the production of B cells. As a result, many fewer genes are required to code for the 10 x 10^6 different kinds of Ab receptors (proteins) on B cells.
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duddyduddy
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